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Cytochrome CYP2D6 is impaired most by fluoxetine and least by sertraline and is the isozyme most responsible for metabolism of tricyclic antidepressants!

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At 3 months, the proportions of patients who had recovered facial function were 830% in the prednisolone group as compared with 636% among patients who did not receive prednisolone (P<0001) and 712% in the acyclovir group as compared with 757% among patients who did not receive acyclovir (adjusted P=050). Tretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition!

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